Transcriptional targeting of virus-mediated gene transfer by the human hexokinase II promoter
نویسندگان
چکیده
منابع مشابه
Hexokinase II gene: structure, regulation and promoter organization.
Lynch, R. M., Fogarty, K. E. and Fay, F. S. (1991) J. Cell Biol. 112, 385-395 Lynch, R. M., Carrington, W., Fogarty, K. E. and Fay, F. S. (1996) Am. J. Physiol. 270, C488-C499 de Cerqueira Cesar, M. and Wilson, J. E. (1995) Arch. Biochem. Biophys. 324,9-14 Katzen, H. M., Soderman, D. D. and Wiley, C. E. (1970) J. Biol. Chem. 245,4081-4096 Kurokawa, M., Oda, S., Tsubotani, E., Fujiwara, H., Yoki...
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We examined the ability of the human surfactant protein B (SP-B) promoter to confer cell specificity of transgene expression in an adenoviral vector. Using similar replication-deficient adenoviruses (rAd), we compared lacZ reporter gene expression driven by the human SP-B promoter (rAd.SPBlacZ) with the ubiquitously expressed Rous sarcoma virus promoter (rAd.RSVlacZ). rAd.SPBlacZ expressed lacZ...
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15 صفحه اولTranscriptional regulation of the human hepatic lipase (LIPC) gene promoter.
Hepatic lipase (HL) plays a key role in the metabolism of plasma lipoproteins, and its level of activity requires tight regulation, given the association of both low and high levels with atherosclerosis and coronary artery disease. However, little is known about the factors responsible for HL expression. Here, we report that the human hepatic lipase gene (LIPC) promoter is regulated by hepatocy...
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The cytokine interleukin-7 (IL-7) has essential growth activities that maintain the homeostatic balance of the immune system. Little is known of the mechanism by which IL-7 signaling regulates metabolic activity in support of its vital function in lymphocytes. We observed that IL-7 deprivation caused a rapid decline in the metabolism of glucose that was attributable to loss of intracellular glu...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2006
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.18.5.901